潜在的なBPC-157およびTB-500Synergy in wundrepair研究により、BPC-157とTB-500は、両方とも創傷治癒を刺激するのに役立ち、異なる生化学経路を組み合わせると相乗効果がある可能性があることが明らかになりました。細胞移動創傷治癒の成功は、免疫系の細胞と同様に細胞外マトリックスの産生を調節する線維芽細胞に依存します。これらの細胞が彼らの仕事をするために、彼らは怪我の場所に移動することを考えていません。移動と呼ばれるこの動きは、タンパク質アクチンに大きく依存しています。 BPC-157とTB-500はどちらも、アクチンの産生を増加させるためのアクチン調節BPC-157作業において重要です[1]。一緒に、BPC-157とTB-500は、アクチンの量と機能を増加させ、免疫系の線維芽細胞と細胞の速度を損傷の領域に移動するために、労働率が合わせます。Big Picture Involves成長ホルモンTB-500とBPC-157の両方が、治癒プロセスで成長ホルモンと相互作用します。 BPC-157は、線維芽細胞上の成長ホルモン受容体の発現を増加させ、これらの細胞の視力を高め、したがって軟部組織の再生を促進する能力を高めます[3]。搭載されている搭載では、追加の成長ホルモン受容体は無駄になりません。これは、細長い寿命を使用するために、細長い寿命を利用するためのアクチンの適切な貯蔵を備えているため、廃棄物になりません。著者について上記の文献は、M.D。Dr。E. Logan博士によって研究、編集、および組織されました。分子生物学で。科学ジャーナの著者Allan L. Goldstein, MD, Allan L. Goldstein is professor and Catharine B. & WiliamMcCormick Chair of the department of Biochemistry and Molecular Biology at TheGeorge Washington University School of Medicine and Health Sciences, where he hasserved since 1978. Thymosins were discovered in the mid 1960’s, when Allan Goldsteinfrom the Laboratory of Abraham White at the Albert Einstein College of Medicine in NewYork studied the role of the thymus in development of the vertebrate immune system. Heis a world-renowned authority on the thymus gland and the workings of the immunesystem, and co-discoverer of the thymosins. Dr. Goldstein is the author of over 400 scientific articles in professional journals, the inventor on more than 15 U.S. Patents, andthe editor of several books in the fields of biochemistry, biomedicine, immunology andneuro-science. He is on the editorial boards of numerous scientific and medical journalsand has been a consultant to many re-search organizations in industry and government;,co-founder of The institute for Advanced Studies in Aging and Geriatric Medicine, a non-profit research and educational institute; a member of the Board of Trustees of the AlbertSabin Vaccine Institute, and serves as the Chairman of the Board of Regene Rx Biopharmaceuticals. Dr. Goldstein received his B.S. from Wagner College in 1959 and hisM.S. and Ph.D. from Rutgers University in 1964. He served as a faculty member of theAlbert Einstein College of Medicine from 1964 to 1972, and moved to the University ofTexas Medical Branch in Galveston in 1972 as professor and director of the division of Biochemistry.
Allan L. Goldstein, MD is being referenced as one of the leading scientists involved in theresearch and development of TB-500 and other Thymosins. In no way is thisdoctor/scientist endorsing or advocating the purchase, sale, or use of this product for anyreason. There is no affiliation or relationship, implied or otherwise, between PeptideSciences and this doctor. The purpose of citing the doctor is to acknowledge, recognize.and credit the exhaustive research and development efforts conducted by the scientistsstudying this peptide. Dr. Goldstein is listed in [5]under the referenced citations.リソース1.C.-H. Chang, W.-C. Tsai, M.-S. Lin, Y-H. Hsu, and J.-H. S. Pang, “The promotingeffect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth,cell survival, and cell migration,”J.Appl. Physiol., vol. 110, no.3, pp.774-780, Oct[Physiology.org]
2.J. Kim and Y. Jung, “Potential Role of Thymosin Beta 4 in Liver Fibrosis,” Int. J.Mol. Sci., vol.16,no.5,pp.10624-10635,May 2015.[NCBI]
3.C.-H. Chang, W.-C. Tsai, Y.-H. Hsu, and J.-H.S.Pang,“Pentadecapeptide BPC157 enhances the growth hormone receptor expression in tendon fibroblasts,” Mol.Basel Switz.,vol.19,no.11,pp.19066-19077, NOV. 2014.[NCBI]
4.Song, Ran & Choi, Hyun & Yang, Hyung-In & Yoo, Myung & Park, Yong-Beom &Kim, Kyoung.(2012).Association between serum thymosin B4 levels of rheumatoidarthritis patients and disease activity and response to therapy. Clinicalrheumatology.31.1253-8.10.1007/s10067-012-2011-7.[Research Gate]
5.Philp, D., et al. “Thymosin β4 Promotes Angiogenesis, Wound Healing, and HairFollicle Development.”Mechanisms ofAgeing and Development, vol. 125, no. 2Feb.2004,pp.113-115,10.1016/i.mad.2003.11.005.[PubMed]
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